Lumbosacral spina bifida cystica with craniovertebral anomalies: report of two cases presenting with neurological disorder in adult life.

Neurological disorders associated with spina bifida are usually either present at birth or arise in early life. There are two main types. First, lesions of the cauda equina; secondly, lesions at the foramen magnum. Occasionally, symptoms do not make their appearance until adult life and then the developmental nature of the disorder may not be recognized. We propose to give an account of two patients with both lumbosacral spina bifida cystica and craniovertebral anomalies who developed a neurological disorder in adult life as a result of lesions of the cerebellum and brain-stem respectively. We are not aware of any previous record of this association.